Kopper László, Tímár József
Semmelweis Egyetem, I. Kórbonctani és Kísérleti Rákkutató Intézet, II. Patológiai Intézet
Cell proliferation and cell death (mainly apoptosis) have programs forming a network to maintain the functional integrity of the organism. Apoptosis has an external and internal units with ligands, signalling pathways and targets. Besides, some other participants (e.g. p53) are involved in the regulation of cell death. Although, apoptosis is a multitargeted process, there is no useful therapy, if it is needed, to correct accumulation of unwanted cells.