Semmelweis Egyetem, ÁOK II. Sz. Gyermekgyógyászati Klinika
Mesenchymal cells can be differentiated into skeletal muscle, smooth muscle, adipose tissue, ﬁbrous tissue, bone and cartilage. Tumors can be originated from these tissues as benign tumors – ﬁ broma, lipoma, osteoma, chondroma, haemangioma, myoma, etc. or as malignant tumors – in childhood, most commonly rhabdomyosarcomas, osteosarcoma, Ewing sarcoma, less often ﬁ brosarcoma, liposarcoma or other rare types. Clinically, the outcome of these tumors have improved signiﬁ cantly in the last decade due to the use of multi-modality treatment (chemotherapy, surgery, irradiation, in some cases targeted therapy). The better treatment results are based on early diagnosis and adequate management according to international treatment protocols in pediatric oncology centers.